biosignal with clinical relevance. biosignal with clinical relevance. Instructions: Pick a biosignal with clinical relevance. Explain what it is used for clinically. What are the characteristics of the signal—amplitude, frequency if periodic, type of signal (e.g., electrical voltage, current, resistance, temperature, displacement, concentration, photons, etc.) and units (Volts, Ohms, Amperes, degrees Celsius, mm, femtoMolar, light intensity, etc.). What disease(s) or pathology/pathologies does the biosignal indicate? What ranges of the biosignal are normal vs. abnormal? Using the libraries portal into pubmed or web of science, find out about the disease state fundamentals from a review article. List as many interesting and relevant facts as you can about the disease state, and cite the review article. Then, find 3 articles that describe different ways to measure the biosignal. An alternative option to a peer-reviewed article is a commercial product with a specification sheet and/or instructions manual. List the top 5 design requirements for a new instrument that would measure the biosignal, based on the clinical need. For each instrument, explain how the signal is sensed, filtered, conditioned, amplified, digitized, and displayed. Cite the 3 peer-reviewed articles for each of these explanations. Come up with a new design of an instrument to detect the biosignal. Make a block diagram or schematic that traces the signal through the sensor, and all processing steps through to the display. Come up with a preliminary parts list where you list the part number and manufacturer. How are the parts linked together (circuit board, cables, wiring, etc.). Finally, explain why your new design fulfills the design requirements. What are potential sources of error, or potential design flaws?
Characteristics (2), units (2), uses (2).
Disease state fundamentals
Fifteen cited facts (1 pt each).
Normal range (2 pts), abnormal range (2 pts).
3 research articles/commercial instruments
2 pts each. All must be relevant to the biosignal and disease/pathology.
5 design requirements
1 pt each. These must be clearly important functionalities that can be addressed by instrumentation choices: for example, cost, sensitivity, accuracy, ease of use.
Signal flow and processing
For each of the 3 designs: explain features of the signal (1), conditioning (1), digitization (1), and display (1).
New design—block diagram
Flow from signal detection to display is fully explained (6 pts), all steps labeled correctly and in an order that makes sense. Insert picture from a powerpoint slide.
Parts with numbers and manufacturer (3), explanation how linked (3).
Design requirements fulfilled
Good explanation for new instrument fulfilling each design requirement (2 pts each).
Sources of error/flaws
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